Notice that it has no single player. Some people may argue that not having single player will hurt the sales of the game but if you look at all of the top games according to Gamespy's stats
Megatextures. Technology that will allow textures to determine how an object acts. Paint a polygon as a blade of grass, and it will sway in the wind. Unique classes for each side. Obviously not as involved as TSA vs. Kharaa or Night Elves vs. Undead, but a hell of a lot better than Red vs. Blue. No "gametypes." Each level will be built around objectives that each team must complete. Leave the flags at home. Online only. No single player, no bots
then a good multiplayer game is really what gives a game it's staying power. Who would have guessed that the most popular game today would still be Counter-Strike?!